PULMONARY FIBROSIS IS A KEY DRIVER OF MORTALITY ACROSS MANY ILDs, INCLUDING CTD-ILDs1

See the connection
WHILE ILDs CAN BE CATEGORIZED BY THEIR ETIOLOGY, THEY CAN BE FURTHER CLASSIFIED ACCORDING TO OBSERVED PATTERNS OF DISEASE BEHAVIOR2,3
When any ILD shows signs of progressive fibrosis, it can be classified as progressive fibrosing-interstitial lung disease (PF-ILD)1,4
Diagram Classification Diagram Classification
PF-ILDs share common fibrotic pathways that become self-sustaining and lead to the irreversible destruction of lung architecture4
Diagram Classification
See how PF-ILD advances via common fibrotic pathways

References: 1. Wells AU et al. Eur Respir J. 2018;0:1-12. 2. Travis WD et al. Am J Respir Crit Care Med. 2013;188(6):733-748. 3. European Respiratory Society Lung White Book. Interstitial lung diseases. In: European Lung White Book. https://www.erswhitebook.org/chapters/interstitial-lung-diseases/. Accessed August 29, 2018. 4. Flaherty KR et al. BMJ Open Resp Res. 2017;4(1):1-7.