OVERVIEW

Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology that has a wide array of organ involvement.1,2

SLE commonly affects:1

  • Joints
  • Skin
  • Kidneys
  • Serous membrane
  • Vessels
  • Central nervous system
  • Respiratory system

EPIDEMIOLOGY

An estimated 161,000 - 322,000 people are living with SLE in the United States, while another 3250 - 81,250 will receive a new diagnosis this year.3-6

Onset of disease typically occurs in individuals between the ages of 15 and 44.7

RISK FACTORS AND MORTALITY

RISK FACTORS:7

  • Women are 7-15 times more likely to develop the disease than men
  • Certain ethnic backgrounds have higher incidence:
    • African American/African Caribbean
    • Asian
    • Hispanic

MORBIDITY/MORTALITY9

  • Men have worse outcomes when they get SLE, including a higher 1-year mortality rate

See also

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Interstitial lung disease in systemic sclerosis with a focus on chest CT

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